Well I prefer JFK, and if Jetblue is an option go for it. It is so much less hassle as they have their own terminal. A taxi is usually $45 to anywhere in Manhattan plus tolls, and you don't have to book ahead. When you leave the airport you wait in a taxi line (usually fast). The other option is the Airtrain, but honestly with 2 ppl and luggage, you'll save time and money taking a flat rate cab.The Late Show has a lottery for tickets, or for most tapings of shows you can turn up at around 4pm and try for standby, but don't count on it. Before moving here, I stayed at the Hotel Pennsylvania because it was right across from Penn Station, Madison Square Gardens, and it was affordable, clean, and large. In NY you have to think, how often will you really be in the room? Plan on taking cabs most places, its just convenient. If you're adventurous though you can access the subway map online and get an idea of how it runs, you would save some $ doing that.And cost..... NY is grand..... you could spend as little as about $500 in a week if you eat two meals a day and take the trains, or you could spend $1 million if you so desire. It is up to you. If you like to shop, buy things from vendors, etc. plan on at least $1,500 for both of you. Manhattan is only 22 miles from tip to tip so no matter how far things are, they never are really that far. Accept that you will not be able to see everything, but make a list of the top 10 things you want to see and stick to it. If it were me...1. Statue of Liberty2. Central Park3. a Broadway show4. Times Square5. Rockafellar Center6. Empire State Bldg7. Brooklyn Bridge8. Museum of Natural History (with the big TRex skeleton!)9. a Bagel sandwich every morning10. ride the subwayI personally love Carmine's for a restaurant, and it is right next to Broadway shows. The portions are family style, so COME HUNGRY!