Since you're older than 35, you have an increased risk of a chromosomal abnormality or genetic disease. Which means, the baby can have neural tube defects such as spina bifida. Miscarriage is the biggest risk of an amnio, occurring in anywhere from 1/200 to 1/400 cases. Be sure to ask the doctor who will peform the test what his/her miscarriage rate is; it may be considerable lower-or higher-than these averages. I hope you nothing but goodluck.