The Sears Tower is located in the southwest section of downtown, approximately 1 mile west of Lake Shore Drive.Geno's has multiple locations. The closest are approximately 1 mile north of downtown and less than 2 miles west of Lake Shore Drive.The Museum of Science and Industry is approximately 8 miles south of downtown and within walking distance of Lake Shore Drive.Since you requested hotels close to the water and near Lake Shore Drive, I picked some near downtown locations that are within walking distance of downtown and shopping. Geno's and Sears are within 2 miles of these locations. But the Museum is 8 miles south. Visit the source links I posted below and check them out. I never stayed at any of them because I live nearby.Hotels in the summertime and near the lake charge premium prices. If they are too high in price, then you will have to google search for hotels in zip codes 60601, 60611, and 60604.