It doesn't matter what form of vitamins one takes, 2 important factors determine its effectiveness. 1 is absorption 2 is potencyI would only prefer Isotonix line whenever it is available because it's the only isotonic form of supplements in the market that provides superior absorption rate that other form cannot beat.In order to form pills, filling, additives needs to be added, these are waste to our body and increase digestion time.In additions, no matter if we drink, eat or take pills, everything need to be broken down into isotonic solution in our stomach first before our body can absorb. Stomach is very high acidic, thus most of the nutrients are destroyed in our stomach before reaching small intestine for absorption. So with pill form, you are looking for absorption rate of about 10 to 40% depending on our body's digestion ability and the ingredients to form the pills. Please keep in mind that human's digestion ability decease by age. With Isotonix line, since it's in isotonic form by adding certain amount of water to one capful of powder (it tastes great too!), vitamin won't stay in stomach and will go to intestine within 5 minutes so you are looking for absorption rate of 90% and higher, higher absorption rate even compare to IV injection.No filling or binding are added to the Isotonix line so you are guarantee to have best potency for the vitamin you take.